Pub. Date : 2014 Jul
PMID : 24778456
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we show that H2S attenuates DNA damage in human endothelial cells and fibroblasts by S-sulfhydrating MEK1 at cysteine 341, which leads to PARP-1 activation. | Cysteine | poly(ADP-ribose) polymerase 1 | Homo sapiens |
| 2 | Mutation of MEK1 cysteine 341 inhibits ERK phosphorylation and PARP-1 activation. | Cysteine | poly(ADP-ribose) polymerase 1 | Homo sapiens |