Title : Alpha-synuclein oligomerization in manganese-induced nerve cell injury in brain slices: a role of NO-mediated S-nitrosylation of protein disulfide isomerase.

Pub. Date : 2014 Dec

PMID : 24777576






1 Functional Relationships(s)
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1 To explore whether alpha-synuclein oligomerization was associated with S-nitrosylation of PDI, we made the rat brain slice model of manganism and pretreated slices with L-Canavanine, a selective iNOS inhibitor. Canavanine nitric oxide synthase 2 Rattus norvegicus