Pub. Date : 2014 Jun 1
PMID : 24775307
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Using proprietary methodology, the high-affinity pyridine or imidazole metal-binding group found in current clinical CYP17 inhibitors was replaced with novel, less avid, metal-binding groups in concert with potency-enhancing molecular scaffold modifications. | pyridine | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |