Title : Activation of peroxisome proliferator-activated receptor β/δ attenuates acute ischemic stroke on middle cerebral ischemia occlusion in rats.

Pub. Date : 2014 Jul

PMID : 24774438






1 Functional Relationships(s)
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1 RESULTS: The pretreatment with GW0742 significantly increased the expression of Bcl-2, and significantly decreased in the volume of infarction, NDS, edema, expressions of IL-1beta, NF-kappaB, TNFalpha, and Bax, contents of iNOS and the apoptotic cells in infarct cerebral hemisphere compared with rats in the vehicle group at 24 hours after MCAO. GW0742 interleukin 1 beta Rattus norvegicus