Title : Inhibitors of signal peptide peptidase (SPP) affect HSV-1 infectivity in vitro and in vivo.

Pub. Date : 2014 Jun

PMID : 24768597






1 Functional Relationships(s)
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1 In this study we have demonstrated for the first time that inhibitors of SPP, such as L685,458, (Z-LL)2 ketone, aspirin, ibuprofen and DAPT, significantly reduced HSV-1 replication in tissue culture. dapt histocompatibility minor 13 Homo sapiens