Title : Berberine ameliorates renal interstitial fibrosis induced by unilateral ureteral obstruction in rats.

Pub. Date : 2014 Sep

PMID : 24754438






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Berberine treatment significantly ameliorated UUO-induced inflammation, and decreased TGF-beta1, pSmad3 and alpha-SMA expression of UUO kidneys. Berberine transforming growth factor, beta 1 Rattus norvegicus
2 CONCLUSION: Berberine treatment ameliorates RIF in a UUO rat model by inhibition of oxidative stress, inflammatory responses, and TGF-beta1/pSmad3 signalling. Berberine transforming growth factor, beta 1 Rattus norvegicus