Title : Proteasome inhibition-induced downregulation of Akt/GSK-3β pathway contributes to abnormality of tau in hippocampal slice.

Pub. Date : 2014 Dec

PMID : 24752588






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1 In this study, proteasome inhibitor MG132 was used to treat hippocampal slices to explore the role and mechanism of Akt/glycogen synthase kinase-3beta (GSK-3beta) in proteasome inhibition-induced tau abnormality. benzyloxycarbonylleucyl-leucyl-leucine aldehyde glycogen synthase kinase 3 beta Homo sapiens