Title : Aggregate culture of human embryonic stem cell-derived hepatocytes in suspension are an improved in vitro model for drug metabolism and toxicity testing.

Pub. Date : 2014 Jul

PMID : 24752503






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here, we present a simple suspension culture of aggregates of ES cell-derived hepatocytes that compared to conventional monolayer adherent culture significantly increases induction of CYP 1A2 by omeprazole and 3A4 by rifampicin. Rifampin cytochrome P450 family 1 subfamily A member 2 Homo sapiens