Title : Niclosamide enhances ROS-mediated cell death through c-Jun activation.

Pub. Date : 2014 Jun

PMID : 24750999






2 Functional Relationships(s)
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1 The combined treatment induced significantly more phosphorylation of p38 MAPK and c-Jun in H1299 cells than IR or niclosamide alone. Niclosamide mitogen-activated protein kinase 14 Homo sapiens
2 Our findings suggest that niclosamide could be a promising radiosensitizer in lung cancer patients through activation of the p38 MAPK-c-Jun axis. Niclosamide mitogen-activated protein kinase 14 Homo sapiens