Title : Hsp70 regulates the doxorubicin-mediated heart failure in Hsp70-transgenic mice.

Pub. Date : 2014 Nov

PMID : 24748476






2 Functional Relationships(s)
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1 The study in primary embryonic cell lines showed that the apoptosis after incubation with DOX was reduced in cells overexpressing Hsp70 (Tg/Tg), while the apoptotic pathway that was activated by DOX administration involved activated protein factors such as p53, Bax, caspase-9, caspase-3, and PARP-1. Doxorubicin BCL2-associated X protein Mus musculus
2 The study in primary embryonic cell lines showed that the apoptosis after incubation with DOX was reduced in cells overexpressing Hsp70 (Tg/Tg), while the apoptotic pathway that was activated by DOX administration involved activated protein factors such as p53, Bax, caspase-9, caspase-3, and PARP-1. Doxorubicin BCL2-associated X protein Mus musculus