Title : Triptolide induces apoptotic cell death of human cholangiocarcinoma cells through inhibition of myeloid cell leukemia-1.

Pub. Date : 2014 Apr 17

PMID : 24742042






2 Functional Relationships(s)
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1 Using quantitative real-time PCR, western blot and immunofluorescence, we have shown that triptolide downregulates Mcl-1 mRNA and protein levels. triptolide MCL1 apoptosis regulator, BCL2 family member Homo sapiens
2 CONCLUSIONS: Triptolide has profound antitumor effect on CCA, probably by inducing apoptosis through inhibition of Mcl-1. triptolide MCL1 apoptosis regulator, BCL2 family member Homo sapiens