Pub. Date : 2014
PMID : 24740347
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Treatment with low doses of salinomycin in combination with TRAIL augmented the activation of caspase-3 and increased TRAIL-R2 cell surface expression. | salinomycin | TNF receptor superfamily member 10b | Homo sapiens |
2 | TRAIL-R2 upmodulation was required for mediating the stimulatory effect of salinomycin on TRAIL-mediated apoptosis, since it was abrogated by siRNA-mediated TRAIL-R2 knockdown. | salinomycin | TNF receptor superfamily member 10b | Homo sapiens |
3 | TRAIL-R2 upmodulation was required for mediating the stimulatory effect of salinomycin on TRAIL-mediated apoptosis, since it was abrogated by siRNA-mediated TRAIL-R2 knockdown. | salinomycin | TNF receptor superfamily member 10b | Homo sapiens |