Title : Activation of GPER-1 estradiol receptor downregulates production of testosterone in isolated rat Leydig cells and adult human testis.

Pub. Date : 2014

PMID : 24736568






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 E2-dependent activation of GPER-1 lowers testosterone production in isolated rats LCs and in human testis, with statistically and clinically significant drops in testosterone production by 20-30% as compared to estradiol-naive LC. Estradiol G protein-coupled estrogen receptor 1 Rattus norvegicus