Title : Profile of vintafolide (EC145) and its use in the treatment of platinum-resistant ovarian cancer.

Pub. Date : 2014

PMID : 24729732






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Vintafolide is a folate-desacetylvinblastine monohydrazide conjugate, allowing a liberation of the drug into the cytoplasm of cancerous cells via the FR-alpha (FRalpha) and endocytosis, with high specificity. Folic Acid FOS like 1, AP-1 transcription factor subunit Homo sapiens
2 Vintafolide is a folate-desacetylvinblastine monohydrazide conjugate, allowing a liberation of the drug into the cytoplasm of cancerous cells via the FR-alpha (FRalpha) and endocytosis, with high specificity. Folic Acid FOS like 1, AP-1 transcription factor subunit Homo sapiens