Title : Divergent signaling mechanisms for venous versus arterial contraction as revealed by endothelin-1.

Pub. Date : 2015 Sep

PMID : 24726828






2 Functional Relationships(s)
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1 Similarly, whereas the PKC inhibitor chelerythrine (10 muM) attenuated ET-1-induced contraction in vena cava and aorta (5% +- 2% and 50% +- 5% of control, respectively; P < .05), only the vena cava contracted to the DAG analogue 1-oleoyl-2-acetyl-sn-glycerol. Diglycerides endothelin 1 Rattus norvegicus
2 Rather, DAG:not IP3:may contribute to contraction to ET-1 in vena cava, in part by activation of PKC. Diglycerides endothelin 1 Rattus norvegicus