Pub. Date : 2014 Mar
PMID : 24716415
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Curcumin induces apoptosis via simultaneously targeting AKT/mTOR and RAF/MEK/ERK survival signaling pathways in human leukemia THP-1 cells. | Curcumin | mitogen-activated protein kinase kinase 7 | Homo sapiens |
| 2 | Curcumin significantly inhibited the activations of AKT/mTOR and RAF/MEK/ERK signaling pathways simultaneously. | Curcumin | mitogen-activated protein kinase kinase 7 | Homo sapiens |
| 3 | CONCLUSION: This study demonstrates that curcumin inhibits proliferation and induces apoptosis in THP-1 cells via inhibiting the activations of AKT/mTOR and RAF/MEK/ERK signaling pathways simultaneously. | Curcumin | mitogen-activated protein kinase kinase 7 | Homo sapiens |