Pub. Date : 2014 Jun
PMID : 24715151
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Doxorubicin induces drug resistance and expression of the novel CD44st via NF-kappaB in human breast cancer MCF-7 cells. | Doxorubicin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | In the present study, we verified that MCF-7 cells subjected to drug pressure develop multidrug resistance to doxorubicin, and the expression levels of multidrug resistance protein 1 (MDR1), CD44st and nuclear factor-kappaB (NF-kappaB) mRNA and protein were gradually upregulated in a dose-dependent manner in MCF-7 cells treated with doxorubicin. | Doxorubicin | nuclear factor kappa B subunit 1 | Homo sapiens |