Title : MLN4924, an NAE inhibitor, suppresses AKT and mTOR signaling via upregulation of REDD1 in human myeloma cells.

Pub. Date : 2014 May 22

PMID : 24713927






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Combining MLN4924 with the proteasome inhibitor bortezomib induces synergistic apoptosis in MM cell lines which can overcome the prosurvival effects of growth factors such as interleukin-6 and insulin-like growth factor-1. Bortezomib interleukin 6 Homo sapiens