Title : Changes in endocannabinoid receptors and enzymes in the spinal cord of SOD1(G93A) transgenic mice and evaluation of a Sativex(®) -like combination of phytocannabinoids: interest for future therapies in amyotrophic lateral sclerosis.

Pub. Date : 2014 Sep

PMID : 24703394






1 Functional Relationships(s)
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1 CONCLUSIONS: Our results demonstrated changes in endocannabinoid signaling, in particular a marked up-regulation of CB2 receptors, in SOD1(G93A) transgenic mice, and provide support that Sativex( ) may serve as a novel disease-modifying therapy in ALS. Endocannabinoids superoxide dismutase 1, soluble Mus musculus