Title : Whole-exome sequencing reveals TopBP1 as a novel gene in idiopathic pulmonary arterial hypertension.

Pub. Date : 2014 May 15

PMID : 24702692






1 Functional Relationships(s)
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Protein Name
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1 Although TopBP1 deficiency made endothelial cells susceptible to DNA damage and apoptosis in response to hydroxyurea, its restoration resulted in less DNA damage and improved cell survival. Hydroxyurea DNA topoisomerase II binding protein 1 Homo sapiens