Protein Name DNA topoisomerase II binding protein 1
Organism Homo sapiens
Gene ID 11073
Gene Symbol

TOPBP1

UniProt Q92547 (TOPB1_HUMAN), A0AV47 (A0AV47_HUMAN), A7E2X7 (A7E2X7_HUMAN), Q05BV8 (Q05BV8_HUMAN)
Relationships Total Number of functionally related compound(s) : 41
Total Number of Articles : 51
Description

DNA topoisomerase II binding protein 1

Gene Summary

This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008]

synonyms
  • DNA topoisomerase 2-binding protein 1
  • DNA topoisomerase II-beta-binding protein 1
  • topoisomerase (DNA) II binding protein 1
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Properties