Title : Genistein increases glycosaminoglycan levels in mucopolysaccharidosis type I cell models.

Pub. Date : 2014 Sep

PMID : 24699889






2 Functional Relationships(s)
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1 Genistein has been shown previously to inhibit GAG synthesis in MPS fibroblasts, presumably through inhibition of tyrosine kinase activity of the epidermal growth factor receptor (EGFR). Glycosaminoglycans epidermal growth factor receptor Homo sapiens
2 This suggests that GAG synthesis is not exclusively regulated through the tyrosine kinase activity of the EGFR. Glycosaminoglycans epidermal growth factor receptor Homo sapiens