Title : Drug transport mechanism of oral antidiabetic nanomedicines.

Pub. Date : 2014 Jan

PMID : 24696697






2 Functional Relationships(s)
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1 EVIDENCE ACQUISITION: Recent reports have identified and explained the beneficial role of several structural molecules like mucoadhesive polymers (polyacrylic acid, sodium alginate, chitosan) and other copolymers for the efficient transport and release of insulin to its receptors. Alginates insulin Homo sapiens
2 Insulin nanoparticles formed by using alginate and dextran sulfate nucleating around calcium and binding to poloxamer, stabilized by chitosan, and subsequently coated with albumin showed a threefold increase of the hypoglycemic effect in comparison to free insulin in animal models. Alginates insulin Homo sapiens