Title : Epigallocatechin-3-gallate ameliorates seawater aspiration-induced acute lung injury via regulating inflammatory cytokines and inhibiting JAK/STAT1 pathway in rats.

Pub. Date : 2014

PMID : 24692852






2 Functional Relationships(s)
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1 The results showed that EGCG pretreatment significantly improved hypoxemia and histopathologic changes, alleviated pulmonary edema and lung vascular leak, reduced the production of TNF-alpha and IL-1, and increased the production of IL-10 in seawater aspiration-induced ALI rats. epigallocatechin gallate tumor necrosis factor Rattus norvegicus
2 EGCG also prevented the seawater aspiration-induced increase of TNF-alpha and IL-1 and decrease of IL-10 in NR8383 cell line. epigallocatechin gallate tumor necrosis factor Rattus norvegicus