Pub. Date : 2014 Apr
PMID : 24692703
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was performed to determine the change in growth inhibition by celecoxib after inhibition of the ER stress pathway by CHOP small-interfering RNA (siRNA). | Celecoxib | DNA damage inducible transcript 3 | Homo sapiens |
| 2 | RESULTS: Celecoxib triggered an ER stress response in this HNSCC cell line as shown by activation of CHOP, GRP78 and XBP1. | Celecoxib | DNA damage inducible transcript 3 | Homo sapiens |
| 3 | The inhibition of cell proliferation by celecoxib was effectively hindered with CHOP siRNA. | Celecoxib | DNA damage inducible transcript 3 | Homo sapiens |