Title : Differential expression of the main polycyclic aromatic hydrocarbon responsive genes in the extrahepatic tissues of mice.

Pub. Date : 2014 Mar

PMID : 24681596






5 Functional Relationships(s)
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1 Previous reports have demonstrated that 3-methylcholanthrene (3MC) is capable of altering the expression of aryl hydrocarbon receptor (AHR)-regulated genes and antioxidant genes in liver, but little is known about the expression patterns in other tissues. Methylcholanthrene aryl-hydrocarbon receptor Mus musculus
2 Previous reports have demonstrated that 3-methylcholanthrene (3MC) is capable of altering the expression of aryl hydrocarbon receptor (AHR)-regulated genes and antioxidant genes in liver, but little is known about the expression patterns in other tissues. Methylcholanthrene aryl-hydrocarbon receptor Mus musculus
3 Previous reports have demonstrated that 3-methylcholanthrene (3MC) is capable of altering the expression of aryl hydrocarbon receptor (AHR)-regulated genes and antioxidant genes in liver, but little is known about the expression patterns in other tissues. Methylcholanthrene aryl-hydrocarbon receptor Mus musculus
4 Previous reports have demonstrated that 3-methylcholanthrene (3MC) is capable of altering the expression of aryl hydrocarbon receptor (AHR)-regulated genes and antioxidant genes in liver, but little is known about the expression patterns in other tissues. Methylcholanthrene aryl-hydrocarbon receptor Mus musculus
5 To investigate whether similar effects could occur in the extrahepatic tissues, adult male ICR mice were received an intraperitoneal injection of 100 mg/kg 3MC and then analyzed after 6 and 24 h. We observed that the constitutive expression of AHR- and antioxidant-related genes was in a tissue-specific manner. Methylcholanthrene aryl-hydrocarbon receptor Mus musculus