Title : Stimulation of estradiol biosynthesis by tributyltin in rat hippocampal slices.

Pub. Date : 2014

PMID : 24679120






1 Functional Relationships(s)
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1 We found that the estradiol synthesis was stimulated by ~2-fold following a 48-h treatment with 0.1 muM tributyltin, and this was accompanied by transcriptional activation of P450(17alpha) and P450arom. Estradiol cytochrome P450, family 17, subfamily a, polypeptide 1 Rattus norvegicus