Title : Effects of Teratogenic Drugs on CYP1A1 Activity in Differentiating Rat Embryo Cells.

Pub. Date : 2015 May

PMID : 24668578






2 Functional Relationships(s)
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1 The EROD activity increased significantly following LB cells exposure to RA and HC (p<0.05) but the expression of CYP1A1 protein was reduced by these drugs, whereas the expression of CYP1A1 protein and EROD activity decreased significantly following the addition of CA and QN (p<0.05, p<0.01). Quinine cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus
2 The EROD activity increased significantly following LB cells exposure to RA and HC (p<0.05) but the expression of CYP1A1 protein was reduced by these drugs, whereas the expression of CYP1A1 protein and EROD activity decreased significantly following the addition of CA and QN (p<0.05, p<0.01). Quinine cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus