| Protein Name | cytochrome P450, family 1, subfamily a, polypeptide 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24296 |
| Gene Symbol | Cyp1a1 |
| UniProt | P00185 (CP1A1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
920
Total Number of Articles : 1240 |
Description |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
| Gene Summary |
Enables several functions, including flavonoid 3'-monooxygenase activity; heat shock protein binding activity; and oxidoreductase activity, acting on diphenols and related substances as donors. Contributes to oxidoreductase activity. Involved in several processes, including 9-cis-retinoic acid biosynthetic process; hepatocyte differentiation; and xenobiotic metabolic process. Located in mitochondrial inner membrane. Biomarker of end stage renal disease; heart disease; pulmonary hypertension; and renal cell carcinoma. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); diabetes mellitus (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung disease (multiple). Orthologous to human CYP1A1 (cytochrome P450 family 1 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022] |
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