Title : Immunosuppression via adenosine receptor activation by adenosine monophosphate released from apoptotic cells.

Pub. Date : 2014 Mar 25

PMID : 24668173






1 Functional Relationships(s)
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1 A nucleotidase inhibitor and A2a adenosine receptor antagonist inhibited the apoptotic supernatant-induced gene expression, suggesting AMP was metabolized to adenosine by an ecto-5"-nucleotidase expressed on macrophages, to activate the macrophage A2a adenosine receptor. Adenosine Monophosphate 5' nucleotidase, ecto Mus musculus