Title : Characterization of the structural determinants required for potent mechanism-based inhibition of human cytochrome P450 1A1 by cannabidiol.

Pub. Date : 2014 May 25

PMID : 24667653






1 Functional Relationships(s)
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1 When preincubated in the presence of NADPH for 20min, olivetol, which corresponds to the pentylresorcinol moiety of CBD, enhanced the inhibition of the 7-ethoxyresorufin O-deethylase activity of CYP1A1. NADP cytochrome P450 family 1 subfamily A member 1 Homo sapiens