Title : Involvement of diacylglycerol produced by phospholipase D activation in Aβ-induced reduction of sAPPα secretion in SH-SY5Y neuroblastoma cells.

Pub. Date : 2014 Apr 18

PMID : 24650665






1 Functional Relationships(s)
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1 We subsequently examined whether PLD was involved in Abeta-induced reduction of sAPPalpha secretion and showed that 2 muM CAY10593, which selectively inhibits PLD2, ameliorated reduction of sAPPalpha secretion, whereas 50 nM CAY10593, which selectively inhibits PLD1, did not. UNII-042A8N37WH glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens