Title : MiR-29b inhibits collagen maturation in hepatic stellate cells through down-regulating the expression of HSP47 and lysyl oxidase.

Pub. Date : 2014 Apr 18

PMID : 24650661






1 Functional Relationships(s)
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1 In this study we have demonstrated that expression of HSP47 and LOX was significantly up-regulated in culture-activated primary rat hepatic stellate cells (HSCs), TGF-beta stimulated LX-2 cells and liver tissue of CCl4-treated mice, which was accompanied by a decrease of miR-29b level. Carbon Tetrachloride lysyl oxidase Rattus norvegicus