Title : Localization of the inhibitory site(s) of pentosan polysulphate in blood coagulation.

Pub. Date : 1988 Oct 31

PMID : 2464199






3 Functional Relationships(s)
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1 We studied the inhibitory effect of pentosan polysulphate (PPS, Hemoclar) on thrombin formation in blood coagulation. Pentosan Sulfuric Polyester coagulation factor II, thrombin Homo sapiens
2 We studied the inhibitory effect of pentosan polysulphate (PPS, Hemoclar) on thrombin formation in blood coagulation. Pentosan Sulfuric Polyester coagulation factor II, thrombin Homo sapiens
3 We postulate therefore that the antithrombin III independent inhibitory effect of PPS on thrombin generation on blood coagulation is by interaction with factor VIIIa. Pentosan Sulfuric Polyester coagulation factor II, thrombin Homo sapiens