Title : COX-2-independent effects of celecoxib sensitize lymphoma B cells to TRAIL-mediated apoptosis.

Pub. Date : 2014 May 15

PMID : 24637636






1 Functional Relationships(s)
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1 We provide evidence that celecoxib affects proliferation and sensitizes NHL B-cell lines to apoptosis through COX-2-independent effects by slowing down the cell cycle and decreasing the expression of survival proteins, such as Mcl-1. Celecoxib MCL1 apoptosis regulator, BCL2 family member Homo sapiens