Title : Roles of mitochondrial fragmentation and reactive oxygen species in mitochondrial dysfunction and myocardial insulin resistance.

Pub. Date : 2014 May 1

PMID : 24631294






3 Functional Relationships(s)
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Protein Name
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1 When myocytes were exposed to hydrogen peroxide (H2O2), they increased DRP1 expression and mitochondrial fragmentation, resulting in DeltaPsim depolarization and insulin resistance. Hydrogen Peroxide dynamin 1 like Homo sapiens
2 When myocytes were exposed to hydrogen peroxide (H2O2), they increased DRP1 expression and mitochondrial fragmentation, resulting in DeltaPsim depolarization and insulin resistance. Hydrogen Peroxide dynamin 1 like Homo sapiens
3 When DRP1 was suppressed by siRNA, H2O2-induced mitochondrial dysfunction and insulin resistance were restored. Hydrogen Peroxide dynamin 1 like Homo sapiens