Protein Name dynamin 1 like
Organism Homo sapiens
Gene ID 10059
Gene Symbol


UniProt O00429 (DNM1L_HUMAN), B4DYR6 (B4DYR6_HUMAN)
Relationships Total Number of functionally related compound(s) : 227
Total Number of Articles : 322

dynamin 1 like

Gene Summary

This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

  • dynamin-1-like protein
  • Dnm1p/Vps1p-like protein
  • dynamin family member proline-rich carboxyl-terminal domain less
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