Title : Inhibitory effect of ciprofloxacin on β-glucuronidase-mediated deconjugation of mycophenolic acid glucuronide.

Pub. Date : 2014 Jul

PMID : 24615849






5 Functional Relationships(s)
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Protein Name
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1 Ciprofloxacin and phenolphthalein-beta-d-glucuronide (PhePG), a typical beta-glucuronidase substrate, significantly decreased the production of MPA from MPAG in the beta-glucuronidase-mediated deconjugation system. phenolphthalein glucuronide glucuronidase beta Homo sapiens
2 Ciprofloxacin and phenolphthalein-beta-d-glucuronide (PhePG), a typical beta-glucuronidase substrate, significantly decreased the production of MPA from MPAG in the beta-glucuronidase-mediated deconjugation system. phenolphthalein glucuronide glucuronidase beta Homo sapiens
3 Ciprofloxacin and phenolphthalein-beta-d-glucuronide (PhePG), a typical beta-glucuronidase substrate, significantly decreased the production of MPA from MPAG in the beta-glucuronidase-mediated deconjugation system. phenolphthalein glucuronide glucuronidase beta Homo sapiens
4 Ciprofloxacin and phenolphthalein-beta-d-glucuronide (PhePG), a typical beta-glucuronidase substrate, significantly decreased the production of MPA from MPAG in the beta-glucuronidase-mediated deconjugation system. phenolphthalein glucuronide glucuronidase beta Homo sapiens
5 While PhePG inhibited the beta-glucuronidase-mediated production of MPA from MPAG in a competitive manner, ciprofloxacin inhibited MPA synthesis via noncompetitive inhibition. phenolphthalein glucuronide glucuronidase beta Homo sapiens