Title : Activating FLT3 mutants show distinct gain-of-function phenotypes in vitro and a characteristic signaling pathway profile associated with prognosis in acute myeloid leukemia.

Pub. Date : 2014

PMID : 24608088






2 Functional Relationships(s)
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1 The pro-proliferative capacity of the investigated FLT3 mutants was associated with cell surface expression and tyrosine 591 phosphorylation of the FLT3 receptor. Tyrosine fms related receptor tyrosine kinase 3 Homo sapiens
2 The pro-proliferative capacity of the investigated FLT3 mutants was associated with cell surface expression and tyrosine 591 phosphorylation of the FLT3 receptor. Tyrosine fms related receptor tyrosine kinase 3 Homo sapiens