Title : Sinapine as an active compound for inhibiting the proliferation of Caco-2 cells via downregulation of P-glycoprotein.

Pub. Date : 2014 May

PMID : 24607798






4 Functional Relationships(s)
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1 Sinapine as an active compound for inhibiting the proliferation of Caco-2 cells via downregulation of P-glycoprotein. sinapine ATP binding cassette subfamily B member 1 Homo sapiens
2 Immunoblotting and QT-PCR analysis showed that sinapine suppressed P-glycoprotein (P-gp) expression via ubiquitination. sinapine ATP binding cassette subfamily B member 1 Homo sapiens
3 Immunoblotting and QT-PCR analysis showed that sinapine suppressed P-glycoprotein (P-gp) expression via ubiquitination. sinapine ATP binding cassette subfamily B member 1 Homo sapiens
4 These results indicated that sinapine played an important role in the down-regulation of P-gp expression through suppression of FGFR4-FRS2alpha-ERK1/2 signaling pathway. sinapine ATP binding cassette subfamily B member 1 Homo sapiens