Title : Interaction of translationally controlled tumor protein with Apaf-1 is involved in the development of chemoresistance in HeLa cells.

Pub. Date : 2014 Mar 7

PMID : 24606760






1 Functional Relationships(s)
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1 TCTP antagonized the mitochondria-dependent apoptotic pathway following etoposide treatment, including mitochondrial membrane damage and resultant cytochrome c release, activation of caspase-9, and -3, and eventually, the cleavage of EGFR and PLC-gamma. Etoposide epidermal growth factor receptor Homo sapiens