Title : Genetic predisposition to essential hypertension in children: analysis of 17 single nucleotide polymorphisms.

Pub. Date : 2013

PMID : 24605586






2 Functional Relationships(s)
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Protein Name
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1 Two single nucleotide polymorphisms--MMP9 (C(-1562) --> T) and NOS3 (Glu298 --> Asp)--rs3918242 and rs1799983--were shown to represent the main independent effects with the highest predictive potential (77.1% as indicated by binary logistic regression and 74.6% testing accuracy shown by Multifactorial Dimensionality Reduction). Aspartic Acid nitric oxide synthase 3 Homo sapiens
2 MMP9 (C(-1562 --> T) and NOS3 (Glu298 --> Asp) potentially may be used to create predictive algorithm for determination of predisposition to arterial hypertension in children. Aspartic Acid nitric oxide synthase 3 Homo sapiens