Pub. Date : 2014 Dec
PMID : 24588516
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Those results suggest that cetuximab influence irinotecan distribution into tissues probably due to inhibition of P-gp. | Irinotecan | ATP binding cassette subfamily B member 1 | Homo sapiens |
2 | Inhibiting SN-38 efflux by P-gp drug transporters in biliary system and tumour can lead to pharmacokinetic modification and a higher anticancer efficacy. | Irinotecan | ATP binding cassette subfamily B member 1 | Homo sapiens |