Title : Local anesthetics induce apoptosis in human thyroid cancer cells through the mitogen-activated protein kinase pathway.

Pub. Date : 2014

PMID : 24586874






1 Functional Relationships(s)
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1 Lidocaine and bupivacaine caused disruption of mitochondrial membrane potential and release of cytochrome c, accompanied by activation of caspase 3 and 7, PARP cleavage, and induction of a higher ratio of Bax/Bcl-2. Bupivacaine BCL2 apoptosis regulator Homo sapiens