Pub. Date : 2014
PMID : 24586676
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | GSTT1 deletion is related to polycyclic aromatic hydrocarbons-induced DNA damage and lymphoma progression. | Polycyclic Aromatic Hydrocarbons | glutathione S-transferase theta 1 | Homo sapiens |
| 2 | Here we investigated the molecular connection of the genetic polymorphism of GSTT1 to the response of lymphocytes to polycyclic aromatic hydrocarbons (PAH). | Polycyclic Aromatic Hydrocarbons | glutathione S-transferase theta 1 | Homo sapiens |
| 3 | Here we investigated the molecular connection of the genetic polymorphism of GSTT1 to the response of lymphocytes to polycyclic aromatic hydrocarbons (PAH). | Polycyclic Aromatic Hydrocarbons | glutathione S-transferase theta 1 | Homo sapiens |
| 4 | Mimicking environmental exposure using long-term repeat culture with low-dose PAH metabolite Hydroquinone, malignant B- and T-lymphocytes presented increased DNA damage, pCHK1/MYC expression and cell proliferation, which were counteracted by ectopic expression of GSTT1. | Polycyclic Aromatic Hydrocarbons | glutathione S-transferase theta 1 | Homo sapiens |
| 5 | Collectively, these findings suggested that GSTT1 deletion is related to genetic predisposition to lymphoma, particularly interacting with environmental pollutants containing PAH. | Polycyclic Aromatic Hydrocarbons | glutathione S-transferase theta 1 | Homo sapiens |