| Protein Name | glutathione S-transferase theta 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 2952 |
| Gene Symbol | GSTT1 |
| UniProt | P30711 (GSTT1_HUMAN), A0A0G2JRN4 (A0A0G2JRN4_HUMAN), A0A0G2JRQ5 (A0A0G2JRQ5_HUMAN), Q4W251 (Q4W251_HUMAN), Q4GZS9 (Q4GZS9_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
277
Total Number of Articles : 430 |
Description |
glutathione S-transferase theta 1 |
| Gene Summary |
The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
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