Title : Estrogen controls the survival of BRCA1-deficient cells via a PI3K-NRF2-regulated pathway.

Pub. Date : 2014 Mar 25

PMID : 24567396






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Pretreatment of mammary epithelial cells (MECs) with the phosphatidylinositol 3-kinase inhibitor BKM120 abolishes the capacity of E2 to increase NRF2 protein and transcriptional activity. NVP-BKM120 NFE2 like bZIP transcription factor 2 Homo sapiens