Title : Berry anthocyanins suppress the expression and secretion of proinflammatory mediators in macrophages by inhibiting nuclear translocation of NF-κB independent of NRF2-mediated mechanism.

Pub. Date : 2014 Apr

PMID : 24565673






3 Functional Relationships(s)
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1 Interleukin 1beta (IL-1beta) messenger RNA (mRNA) levels were significantly decreased by all berry anthocyanins at 10 mug/ml or higher. Anthocyanins interleukin 1 beta Mus musculus
2 Interleukin 1beta (IL-1beta) messenger RNA (mRNA) levels were significantly decreased by all berry anthocyanins at 10 mug/ml or higher. Anthocyanins interleukin 1 beta Mus musculus
3 However, in the BMM from Nrf2(-/-) mice, the anthocyanin fractions were able to significantly decrease IL-1beta mRNA despite the fact that ROS levels were not significantly affected. Anthocyanins interleukin 1 beta Mus musculus