Title : Secretoneurin induces airway mucus hypersecretion by enhancing the binding of EGF to NRP1.

Pub. Date : 2014

PMID : 24556756






1 Functional Relationships(s)
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1 CONCLUSIONS: We conclude that SN induces MUC5AC hypersecretion in a dose- and time-dependent manner; moreover, the MUC5AC over synthesis induced by SN is strongly associated with the enhanced binding of EGF to NRP1 and the activation of EGFR and ERK1/2 subsequently. Tin mitogen-activated protein kinase 3 Homo sapiens