Title : Cell differentiation versus cell death: extracellular glucose is a key determinant of cell fate following oxidative stress exposure.

Pub. Date : 2014 Feb 20

PMID : 24556689






3 Functional Relationships(s)
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Protein Name
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1 The activities of both forkhead box O (FOXO1) and p53 were required for upregulation of bim RNA expression in high glucose. Glucose tumor protein p53 Homo sapiens
2 High glucose coupled with oxidative stress resulted in upregulation of miR28-5p, which directly inhibited expression of the p53 deacetylase sirtuin 3, resulting in increased levels of acetylated p53. Glucose tumor protein p53 Homo sapiens
3 High glucose coupled with oxidative stress resulted in upregulation of miR28-5p, which directly inhibited expression of the p53 deacetylase sirtuin 3, resulting in increased levels of acetylated p53. Glucose tumor protein p53 Homo sapiens